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Separation，Purification and Identification of Rat Bone Marrow Mesenchymal Stem Cells

Zhang Rongli,Feng Xue,Zhang Huiliang,Luo Guoan,Li Lianda ,Wang Yiming

Strategic Study of CAE 2007, Volume 9, Issue 7,   Pages 89-94

Abstract:

Bone marrow mesenchymal stem cells (BMMSCs) were separated by densityThe cells were verified as the BMMSC by the expression of the CSA and the genes.This is a simple and reliable method to obtain BMMSC as stem cell used in cell and tissue engineering

Keywords： rat     bone marrow mesenchymal stem cells(BMMSCs)     flow cytometry    

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Autologous bone marrow stem cell transplantation for the treatment of ulcerative colitis complicated

Hang Xiang,Xiaomei Zhang,Chao Yang,Wenhuan Xu,Xin Ge,Rong Zhang,Ya Qiu,Wanjun Sun,Fan Li,Tianyuan Xiang,Haixu Chen,Zheng Wang,Qiang Zeng

Frontiers of Medicine 2016, Volume 10, Issue 4,   Pages 522-526 doi: 10.1007/s11684-016-0485-4

Abstract: Therefore, we performed an autologous bone marrow cells to modulate the immune system with his permissionAutologous bone marrow mononuclear cells were collected and injected locally into the bowel mucosa, andAfter the patient underwent auto bone marrow mononuclear cells transplantations twice, the patient&rsquo

Keywords： autograft     bone marrow stem cells     ulcerative colitis     cell therapy    

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the intensity and loading time of direct current electric field on the directional migration of rat bonemarrow mesenchymal stem cells

Xiaoyu Wang,Yuxuan Gao,Haigang Shi,Na Liu,Wei Zhang,Hongbo Li

Frontiers of Medicine 2016, Volume 10, Issue 3,   Pages 286-296 doi: 10.1007/s11684-016-0456-9

Abstract:

Exogenic electric fields can effectively accelerate bone healing and remodeling through the enhancedmigration of bone marrow mesenchymal stem cells (BMSCs) toward the injured area.

Keywords： DCEF     migration     osteogenesis differentiation     rBMSCs     SDF-1/CXCR-4    

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Pluripotent stem cells exhibiting similar characteristics can be isolated from human fetal bone marrow

FANG Baijun, SONG Yongping, LIN Quande, ZHAO Chunhua, SHI Mingxia

Frontiers of Medicine 2007, Volume 1, Issue 2,   Pages 185-191 doi: 10.1007/s11684-007-0035-1

Abstract: Previously, we reported that a cell population derived from human fetal bone marrow (BM), termed hereFlk1CD34 postembryonic pluripotent stem cells (PPSCs) that have the characteristics of mesenchymal stemIn this study, we further isolated pluripotent stem cells from human fetal heart, liver, muscle, lung, derma, kidney, and fat and then analyzed the characteristics and function of these stem cells.Thus, they may be an ideal source of stem cells for treatment of inherited or degenerative diseases.

Keywords： endothelial     phenomenon     ectodermal     Flk1CD34 postembryonic     irradiated non-obese    

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Advances in Autologous Bone Marrow Stem Cell Transplantation

Li Lianda,Wu Limao,Liu Hong,Ning Keyong,Li Yikui

Strategic Study of CAE 2004, Volume 6, Issue 8,   Pages 1-4

Abstract: Bone marrow cells can be easily obtained from adult marrow, opening the possibility of autologous transplantationIt also discusses the current status of autologous bone marrow stem cell transplantation with emphaseson approaches to stem cell mobilization.

Keywords： bone marrow stem cells     autologous transplantation     bone marrow mobilizer    

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Umbilical cord-derived mesenchymal stem cells: strategies, challenges, and potential for cutaneous regeneration

Siming Yang, Sha Huang, Changjiang Feng, Xiaobing Fu

Frontiers of Medicine 2012, Volume 6, Issue 1,   Pages 41-47 doi: 10.1007/s11684-012-0175-9

Abstract:

Umbilical cord mesenchymal stem cells (MSCs) are a unique, accessible, and non-controversial sourceof early stem cells that can be readily manipulated.As the most common pluripotent cell, bone marrow-derived MSCs display limitations with the progress ofstem cell therapy.By contrast, umbilical cord-derived cells, which have plentiful resources, are more accessible.

Keywords： umbilical cord     mesenchymal stem cells     cutaneous regeneration    

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Studies of the Guiyuan Fang and Autologous Bone Marrow Stem Cells Transplantation on Hepatic Injury and

Wu Limao,Li Lianda,Liu Hong,Ning Keyong,Li Yikui

Strategic Study of CAE 2004, Volume 6, Issue 7,   Pages 34-42

Abstract:

Objective To study the anti-fibrotic and anti-injurious activities of TCM and autologous bone marrowstem cells transplantation.transplanted cells were predominantly in clusters of 1～3 cells each.Conclusion The bone marrow stem cells survive, proliferate, and differentiate in the fibrotic and injuriousTCM synergize with bone marrow stem cells to improve liver function, to protect hepatocytes from toxicant

Keywords： bone marrow stem cells     autologous transplantation     liver injury     liver fibrosis     guiyuan fang    

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Mesenchymal stem cells hold promise for regenerative medicine

Shihua Wang, Xuebin Qu, Robert Chunhua Zhao

Frontiers of Medicine 2011, Volume 5, Issue 4,   Pages 372-378 doi: 10.1007/s11684-011-0164-4

Abstract: an emerging interdisciplinary field of research that uses several technological approaches including stemcells to repair tissues.Mesenchymal stem cells (MSCs), a type of adult stem cell, have generated a great amount of interest overmechanisms through which MSCs exert their therapeutic potential rely on some key properties of the cellsinto osteoblasts, chondrocytes, adipocytes, cardiomyocytes, hepatocytes, endothelial, and neuronal cells

Keywords： mesenchymal stem cells     differentiation     immunomodulation     regenerative medicine    

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Implantation of human umbilical cord mesenchymal stem cells for ischemic stroke: perspectives and challenges

Yingchen Li,Guoheng Hu,Qilai Cheng

Frontiers of Medicine 2015, Volume 9, Issue 1,   Pages 20-29 doi: 10.1007/s11684-014-0371-x

Abstract: As a neuroregenerative therapy, the implantation of human umbilical cord mesenchymal stem cells (hUC-MSCs

Keywords： cellular therapy     transplantation     human umbilical cord     mesenchymal stem cells     ischemic stroke    

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Capacity of human umbilical cord-derived mesenchymal stem cells to differentiate into sweat gland-likecells: a preclinical study

Siming Yang, Kui Ma, Changjiang Feng, Yan Wu, Yao Wang, Sha Huang, Xiaobing Fu

Frontiers of Medicine 2013, Volume 7, Issue 3,   Pages 345-353 doi: 10.1007/s11684-013-0282-2

Abstract:

Human umbilical cord-derived mesenchymal stem cells (hUC-MSCs) possess various advantageous propertiespotential, multi-lineage differentiation potential and capacity for differentiating into sweat gland-like cellsculture media (ASFCM) in order to determine their potential for differentiation into sweat gland-like cellsMoreover, cells cultured in ASFCM showed vigorous proliferation comparable to those of cells grown inMorphology of hUC-MSCs cultured in ASFCM was comparable to those of cells grown under classical culture

Keywords： umbilical cord     mesenchymal stem cells     sweat gland     preclinical    

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Transplantation of placenta-derived mesenchymal stem cells in type 2 diabetes: a pilot study

Ranhua JIANG, Zhibo HAN, Guangsheng ZHUO, Xiaodan QU, Xue LI, Xin WANG, Yuankang SHAO, Shimin YANG, Zhong Chao HAN

Frontiers of Medicine 2011, Volume 5, Issue 1,   Pages 94-100 doi: 10.1007/s11684-011-0116-z

Abstract:

Mesenchymal stem cells (MSC) have been used in clinical trials for severe diabetes, a chronic diseaseBone marrow is the traditional source of human MSC, but human term placenta appears to be an alternative

Keywords： placenta stem cells     treatment of type 2 diabetes    

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Regulatory factors of mesenchymal stem cell migration into injured tissues and their signal transduction

Li LI, Jianxin JIANG

Frontiers of Medicine 2011, Volume 5, Issue 1,   Pages 33-39 doi: 10.1007/s11684-011-0114-1

Abstract:

Adult stem cells hold great promise for wound healing and tissue regeneration.Mesenchymal stem cells (MSCs), for example, have been shown to play a role in tissue repair.Research has shown that endogenous bone marrow MSCs or exogenously delivered MSCs migrate to the sitesunderstanding of the molecular mechanisms involved in the migration of MSCs will help us to develop new stem

Keywords： mesenchymal stem cells     migration     molecular mechanisms     signaling pathway    

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FGF13 suppresses acute myeloid leukemia by regulating bone marrow niches

Frontiers of Medicine 2022, Volume 16, Issue 6,   Pages 896-908 doi: 10.1007/s11684-022-0944-z

Abstract: definite role in the development of acute myeloid leukemia (AML) and emphasize its associations with bonemarrow niches.marrow niches.overexpression substantially inhibited the growth and significantly induced the early apoptosis of AML cellsmarrow microenvironment.

Keywords： acute myeloid leukemia     FGF13     prognosis     immune-related genes     bone marrow niches    

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Cell therapy for the treatment of reproductive diseases and infertility: an overview from the mechanism to the clinic alongside diagnostic methods

Frontiers of Medicine 2022, Volume 16, Issue 6,   Pages 827-858 doi: 10.1007/s11684-022-0948-8

Abstract: Besides routine therapeutic methods, stem cells are rapidly being examined as viable alternative therapiesRemarkable progress has been made in understanding the biology and purpose of stem cells.The affected pluripotent stem cells (iPSCs) and mesenchymal stem cells (MSCs) are further studied forthis study discusses current developments in the use of some kinds of MSCs such as adipose-derived stemcells, bone marrow stromal cells, umbilical cord MSCs, and menstrual blood MSCs.

Keywords： infertility     stem cell therapy     mesenchymal stem cells     pluripotent stem cells    

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Extracellular vesicle-carried GTF2I from mesenchymal stem cells promotes the expression of tumor-suppressive

Frontiers of Medicine doi: 10.1007/s11684-023-0999-5

Abstract: Therefore, we selected them for this present study, where the effects of bone marrow mesenchymal stemcell-derived EVs (BMSDs-EVs) enriched with GTF2I were evaluated on the epithelial–to–mesenchymal transitionEctopically expressed GTF2I and FAT1 were found to augment malignant phenotypes of TC cells, EMT, andMSC-EVs could shuttle GTF2I into TPC-1 cells, where GTF2I inhibited TC malignant phenotypes, EMT, and

Keywords： thyroid carcinoma     mesenchymal stem cell     extracellular vesicle     GTF2I     FAT1     CDK4    

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Title Author Date Type Operation

Separation，Purification and Identification of Rat Bone Marrow Mesenchymal Stem Cells

Zhang Rongli,Feng Xue,Zhang Huiliang,Luo Guoan,Li Lianda ,Wang Yiming

Journal Article

Autologous bone marrow stem cell transplantation for the treatment of ulcerative colitis complicated

Hang Xiang,Xiaomei Zhang,Chao Yang,Wenhuan Xu,Xin Ge,Rong Zhang,Ya Qiu,Wanjun Sun,Fan Li,Tianyuan Xiang,Haixu Chen,Zheng Wang,Qiang Zeng

Journal Article

the intensity and loading time of direct current electric field on the directional migration of rat bonemarrow mesenchymal stem cells

Xiaoyu Wang,Yuxuan Gao,Haigang Shi,Na Liu,Wei Zhang,Hongbo Li

Journal Article

Pluripotent stem cells exhibiting similar characteristics can be isolated from human fetal bone marrow

FANG Baijun, SONG Yongping, LIN Quande, ZHAO Chunhua, SHI Mingxia

Journal Article

Advances in Autologous Bone Marrow Stem Cell Transplantation

Li Lianda,Wu Limao,Liu Hong,Ning Keyong,Li Yikui

Journal Article

Umbilical cord-derived mesenchymal stem cells: strategies, challenges, and potential for cutaneous regeneration

Siming Yang, Sha Huang, Changjiang Feng, Xiaobing Fu

Journal Article

Studies of the Guiyuan Fang and Autologous Bone Marrow Stem Cells Transplantation on Hepatic Injury and

Wu Limao,Li Lianda,Liu Hong,Ning Keyong,Li Yikui

Journal Article

Mesenchymal stem cells hold promise for regenerative medicine

Shihua Wang, Xuebin Qu, Robert Chunhua Zhao

Journal Article

Implantation of human umbilical cord mesenchymal stem cells for ischemic stroke: perspectives and challenges

Yingchen Li,Guoheng Hu,Qilai Cheng

Journal Article

Capacity of human umbilical cord-derived mesenchymal stem cells to differentiate into sweat gland-likecells: a preclinical study

Siming Yang, Kui Ma, Changjiang Feng, Yan Wu, Yao Wang, Sha Huang, Xiaobing Fu

Journal Article

Transplantation of placenta-derived mesenchymal stem cells in type 2 diabetes: a pilot study

Ranhua JIANG, Zhibo HAN, Guangsheng ZHUO, Xiaodan QU, Xue LI, Xin WANG, Yuankang SHAO, Shimin YANG, Zhong Chao HAN

Journal Article

Regulatory factors of mesenchymal stem cell migration into injured tissues and their signal transduction

Li LI, Jianxin JIANG

Journal Article

FGF13 suppresses acute myeloid leukemia by regulating bone marrow niches

Journal Article

Cell therapy for the treatment of reproductive diseases and infertility: an overview from the mechanism to the clinic alongside diagnostic methods

Journal Article

Extracellular vesicle-carried GTF2I from mesenchymal stem cells promotes the expression of tumor-suppressive

Journal Article